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General Description
The KITLG (KIT ligand) gene is mapped to human chromosome 12q21.32.
Biochem/Physiol Actions
Stem Cell Factor (SCF), also known as c-Kit ligand (KL), steel factor (SLF) and mast cell growth factor (MGF), is a 30 kDa glycoprotein with broad activities on various tissues, including hematopoietic cells, pigment cells, and primordial germ cells.
Preparation Note
SCF is expressed in human HEK 293 cells as a glycosylated monomer with an apparent molecular mass of 35-45 kDa due to glycosylation. Production in human 293 cells offers authentic glycosylation. Glycosylation contributes to stability in cell growth media and other applications.
Analysis Note
The specific activity was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells (human erythroleukemic indicator cell line).
Sigma-Aldrich Stem Cell Factor Human (SCF, c-Kit ligand)
#Grup produk P110082082
Spesifikasi
| Biological Source | Human |
|---|---|
| Quality Level | 200 |
| Recombinant | Expressed in HEK 293 cells |
| Assay | ≥95% (SDS-PAGE) |
| Form | Lyophilized Powder |
| Potency (ng/mL ED50) | ≤200 |
| Mol Wt (kDa) | dimer 35-45 (glycosylated) |
| Quality | Endotoxin Tested |
| Storage Condition | Avoid Repeated Freeze/Thaw Cycles |
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Informasi Produk
Description
Warning
Storage Class Code: 11 - Combustible SolidsWGK: WGK 3
Flash Point(F): Not applicable
Flash Point(C): Not applicable
Ulasan Produk
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