General Description
The HyStem-HP Cell Culture Scaffold Kit provides an excellent starting point for optimizing the matrix for stem cell culture, where slowly released growth factors are crucial in re-creating a stem cell niche. To affect specific cell performance, growth factors or ECM proteins may be added to the HyStem-HP hydrogel. Unlike animal-derived ECM products, this kit contains three fully chemically defined components, which are nonimmunogenic:
HyStem-HP – a thiol-modified hyaluronan (a major constituent of native ECM), carboxymethyl hyaluronic acid-thiopropanoyl hydrazide (CMHA-S, CMHA-DTPH, carboxymethyl hyaluronic acid-DTPH) with heparinthiopropanoyl hydrazide (HP-DTPH). HyStem-HP (CMHA-DTPH with HP-DTPH) contains 99.7 wt% CMHA-DTPH and 0.3 wt% HP-DTPH.Gelin-S – a thiol-modified gelatin (denatured collagen), carboxymethyl gelatin-thiopropanoyl hydrazide (GTN-DTPH, carboxymethyl gelatin-DTPH)Extralink – a thiol-reactive crosslinker, polyethylene glycol diacrylate (MW = 3,400 g/mole, PEGDA)
Sigma-Aldrich HyStem-HP Cell Culture Scaffold Kit
#Grup produk P110080826
Spesifikasi
| Quality Level | 100 |
|---|---|
| Storage Temperature (°C) | -20 |
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Informasi Produk
Description
Warning
Pictograms: GHS05, GHS07Signal Word: Danger
Hazard Statements: H315 - H317 - H318
Precautionary Statements: P261 - P264 - P272 - P280 - P302 + P352 - P305 + P351 + P338
Hazard Classifications: Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1
Storage Class Code: 10 - Combustible liquids
WGK: WGK 3
Feature
Customizable, well characterized and consistent, Hystem-HP hydrogel cell culture scaffolds provide a complex, three dimensional environment in which cells are able to proliferate, much as they would in vivo. Customizable - each distinct cell type in a multicellular organism has its own unique microenvironment. Hystem-HP offers the flexibility to tailor the environments of cultured cells to mimic their in vivo counterparts and optimize proliferation and differentiation.Synthetic - As a synthetic matrix, Hystem-HP offers greater control of the cellular environment than ambiguous extracted ECM alternatives. All components are well characterized and consistently formulated. Hystem-HP contains Hyaluronic acid (synthetic), Extralink (synthetic), Gelin-S (porcine), Heparin and Water.Biologically accurate - Rich in hyaluronic acid and denatured collagen, the Hystem-HP hydrogel closely mimics the complex three dimensional cellular environments found in life, providing an optimal environment for culturing your cells.
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